Diagonal Component Expansion for Flow-Layer Placement of Flow-Based Microfluidic Biochips

Placement Algorithm for Flow-Based Microfluidic Biochips

Microfluidic biochips revolutionize biology by placing laboratory functionality on a very small chip. The subject of this thesis is a flow-based biochip, which consists of thin channels in which fluids flow. The basic building block of the chip is a valve, which can direct the flow by blocking or unblocking channels. The valves are combined to create components like switches, mixers, and mul-ti...

System-Level Modeling and Synthesis Techniques for Flow-Based Microfluidic Very Large Scale Integration Biochips

Microfluidic biochips integrate different biochemical analysis functionalities on-chip and offer several advantages over the conventional biochemical laboratories. In this thesis, we focus on the flow-based biochips. The basic building block of such a chip is a valve which can be fabricated at very high densities, e.g., 1 million valves per cm 2. By combining these valves, more complex units su...

Fault Tolerant DNA Computing Based on ‎Digital Microfluidic Biochips

   Historically, DNA molecules have been known as the building blocks of life, later on in 1994, Leonard Adelman introduced a technique to utilize DNA molecules for a new kind of computation. According to the massive parallelism, huge storage capacity and the ability of using the DNA molecules inside the living tissue, this type of computation is applied in many application areas such as me...

Fault-Tolerant Architecture Design for Flow-Based Biochips

Digital-Microfluidic Biochips

D igital-micro uidic biochips (DMFBs) are revolutionizing laboratory procedures for point-of-care clinical diagnostics, environmental monitoring, and drug discovery. DMFBs allow bioassay protocols to be scaled down to droplet size. They’re executed by enabling precise control of discrete droplets using a patterned array of electrodes. Biochemistry’s inherent complexity means that operational er...